Microbial Metabolites Synthesis Services

In the space of 60 years, people have learnt to harness the chemical diversity available from microorganisms for the benefit of human health. Penicillin, a fungal metabolite, heralded the beginning of the golden age of antibiotics with hundreds of microbial metabolites being studied as drugs to control bacterial diseases. Treatments for fungal infections, parasitic infestations and a range of cancers followed. Today, microbial metabolites are also used for therapeutic that move beyond controlling infections. Sophisticated enzyme and receptor bioassays have identified as new metabolites that act to regulate rather than kill microbial. The antifungal metabolites in compact selectively inhibit 3-hydroxy-3-methylglutaryl-CoA reductase, an enzyme in the pathway for sterol synthesis. This discovery led to the development of a whole new class of drugs, statins, as lipid-lowering agents in humans. Understanding the biology of organ rejection has led to the discovery of immunosuppressants such as rapamycin, tacrolimus and cyclosporin, which are microbial metabolites. Alfa Chemistry has been deeply engaged in the field of synthesis of microbial metabolites for many years and has rich synthesis experience. We are confident that our microbial metabolites synthesis services will make a significant contribution to your research.

Our Service Scope

Alfa Chemistry is a company specializing in the synthesis of microbial metabolites. Moreover, Alfa Chemistry has a large number of authorized patents. Therefore, Alfa Chemistry can provide microbial metabolites synthesis services according to your needs. Our microbial metabolites synthesis services are as follows.

Our Synthesis Techniques

Alfa Chemistry has mastered not only the traditional chemical synthesis techniques but also the biological fermentation techniques for the synthesis of microbial metabolites. Fermentation is a technique of biological conversion of complex substrates into simple compounds by various microorganisms such as bacteria and fungi. Fermentation has been classified into solid-state fermentation (SSF) and submerged fermentation (SmF) based on the type of substrates used during fermentation. Alfa Chemistry has SSF and SmF techniques, their advantages are as follows.

SSF

SSF utilizes solid substrates, like brans, bagasse, and paper pulp. The main advantage of these substrates is that they are nutrient-rich and can be easily recycled. In this fermentation technique, the substrates are utilized very slowly and steadily, so the same substrates can be used for long fermentation periods. Hence, this technique supports the controlled release of nutrients. SSF is best suited to fungi that require less moisture content.

SmF

SmF utilizes free-flowing liquid substrates, such as molasses and broths. The bioactive compounds are secreted into the fermentation broth. The substrates are quickly consumed, so they need to be constantly replaced/supplemented with nutrients. This fermentation technique is best suited to bacteria that require a high moisture content. An additional advantage of SmF is that the purification of products is easier.

Our Advantages

Alfa Chemistry has been deeply engaged in the field of microbial metabolites synthesis for many years. Our advantages include, but are not limited to the following.

• Alfa Chemistry has competitive service prices to reduce your research costs.
• Alfa Chemistry has a professional biochemistry technical team to ensure the quality of synthetic metabolites.
• Alfa Chemistry has advanced biological fermentation techniques to synthesize various microbial metabolites.
• Alfa Chemistry has reliable pre-sales and after-sales service that is responsible for the products to the end.

Alfa Chemistry is proud to deliver customer-focused microbial metabolites synthesis services. Over the years, customers have turned to us not only for our expertise in innovation but for our reputation for agility and for delivering results on time and under budget. Please contact us if you have questions about microbial metabolites synthesis. We will provide you with professional and high quality services.

Ordering Process

Please kindly note that our products and services are for research use only.