Lignans & Neolignans Analysis Services
Lignans and neolignans are a structurally diverse class of secondary metabolites derived from the oxidative coupling of two or more phenylpropanoid (C₆–C₃) units. They occur widely in vascular plants, seeds, and bark, serving as important defense molecules and signaling agents. Due to their broad pharmacological and nutritional significance—spanning antioxidant, anti-inflammatory, antiviral, and anticancer properties—these metabolites have become an active area of research in both natural product chemistry and functional ingredient development.
At Alfa Chemistry, we provide professional lignans & neolignans analysis services to support researchers and industrial clients engaged in plant metabolomics, quality evaluation, and product innovation. With extensive experience in metabolite profiling, we employ high-performance analytical platforms and validated methods to ensure reliable detection, identification, and quantification of lignans and neolignans in complex biological and botanical matrices.
Analytical Capabilities
Our laboratory integrates LC-MS/MS, GC-MS, and HPLC systems for sensitive, high-resolution analysis. The service covers a broad range of compounds, including:
- Typical lignans: secoisolariciresinol, matairesinol, pinoresinol, lariciresinol
- Representative neolignans: magnolol, honokiol, phillyrin, cubebin, and related derivatives
- Glycosides, methylated derivatives, and oxidative intermediates
- Novel lignan dimers and coupling variants identified in recent studies
Our precise mass accuracy and optimized chromatographic separation allow for confident structural elucidation and quantification, even at trace levels.
Service Scope
- Comprehensive Profiling: Global screening and characterization of lignans and neolignans in plant tissues, foods, and natural extracts.
- Quantitative Determination: Absolute or relative quantification using authentic standards and isotope-labeled internal references.
- Pathway Elucidation: Mapping of lignan biosynthetic or catabolic routes within phenylpropanoid metabolism.
- Differential Analysis: Identification of key metabolic changes in response to environmental or genetic variations.
- Customized Solutions: Method optimization and validation tailored to specific compounds, species, or project objectives.
Applications
Accurate lignan and neolignan profiling provides valuable insights into numerous scientific and industrial areas, including:
- Plant Biochemistry and Defense Research: Understanding lignan accumulation as a protective response to stress.
- Natural Product Discovery: Identifying novel bioactive lignans for drug, nutraceutical, or cosmetic development.
- Food and Herbal Product Quality Control: Ensuring component authenticity, purity, and batch consistency.
- Pharmacological Research: Correlating chemical composition with antioxidant, anti-inflammatory, or anticancer mechanisms.
- Agricultural and Ecological Studies: Evaluating lignan metabolism under varying growth or environmental conditions.
Workflow
- Sample Processing: Extraction and purification from plant materials, seeds, or biological fluids.
- Instrumental Analysis: High-resolution LC-MS/MS, GC-MS, or HPLC detection under optimized conditions.
- Data Interpretation: Structural identification, quantification, and pathway correlation using bioinformatic tools.
- Reporting: Delivery of complete analytical documentation, including chromatograms, spectra, quantitative tables, and detailed explanations.
Why Choose Alfa Chemistry
- Expertise in metabolomics: Decades of experience in small-molecule analysis and secondary metabolite research.
- Advanced technologies: Cutting-edge instrumentation ensuring precision, reproducibility, and sensitivity.
- Comprehensive deliverables: From raw data to interpretive reports ready for publication or regulatory submission.
- Flexible collaboration: Tailor-made workflows for academic, industrial, or product development projects.
- Commitment to quality: Reliable turnaround, cost-effective solutions, and strict data confidentiality.
Alfa Chemistry is dedicated to advancing lignan and neolignan research through innovative analytical science. Our integrated services empower global clients to explore structural diversity, clarify metabolic functions, and accelerate the translation of lignan-based discoveries into real-world applications in medicine, nutrition, and agriculture.
Please kindly note that our products and services are for research use only.
