Flavonoids Analysis Services
Flavonoids are secondary metabolites that are very abundant in plants, fruits, and seeds. They are responsible for the color, fragrance, and flavor characteristics. They comprise several thousand compounds that possess a common C6-C3-C6 skeleton where two aromatic rings (A and B) are linked through a three-carbon bridge that usually, but not always, forms a heterocyclic ring (C) giving rise to a phenylchromane, which in some cases can be opened giving rise to chalcone and dihydrochalcone forms. On the basis of the substitution pattern of ring C, different flavonoids are distinguished, such as flavones, flavonols, flavanones, flavanols, anthocyanins, dihydroflavonols, and isoflavones. In plants, flavonoids perform many functions like regulating cell growth, attracting pollinators insects, and protecting against biotic and abiotic stresses[1]. In humans, these compounds are associated with a large range of health benefits, such as anti-inflammatory, anticancer, cardio-protective, neuroprotective, antibacterial, antidiabetic, antiparasitic, and antiviral properties. These benefits come from their bioactive properties. Qualitative and quantitative analysis is critical to the application of flavonoids. Alfa Chemistry offers flavonoids analysis services. Please contact us if you need help.
Figure 1. Basic structure of flavonoids: phenylchromane (a) and chalcone (b).
Our Service Scope
Alfa Chemistry offers application mechanisms analysis, qualitative and quantitative analysis, data analysis and safety analysis services for various flavonoids. These flavonoids include, but are not limited to the following.
Our Analysis Process
Sample pretreatment
- Solid samples usually need to be homogenized and then dried or frozen in liquid nitrogen.
- Liquid samples are usually first filtered and/or centrifuged, after which the sample is either directly injected into the separation system, or more commonly, the analyte is separated by liquid-liquid extraction or solid-phase extraction.
Separation and detection
- The most commonly used method for separation and detection is column liquid chromatography. Column liquid chromatography of flavonoids is usually carried out in reversed-phase mode, on C8- or C18-bonded silica columns. Gas chromatography, capillary electrophoresis, and thin-layer chromatography are used less frequently than column liquid chromatography.
Identification and structural characterization
- Liquid chromatography-mass chromatography (LC-MS) and on-line liquid chromatography-nuclear magnetic resonance spectroscopy (LC-NMR) are important techniques for the identification of target flavonoids and the structural characterization of unknown compounds. Alfa Chemistry utilizes LC-MS and on-line LC-NMR for the identification and structural characterization of flavonoids.
Our Advantages
Alfa Chemistry has leading technology, first-class research and development as well as analytical equipment, and has established a complete flavonoids service system. Over the years, customers have turned to us not only for our expertise in innovation but for our reputation for agility and for delivering results on time and under budget. Our advantages include, but are not limited to the following.
- Alfa Chemistry has a rigorous extraction procedure to ensure the recovery of flavonoids.
- Alfa Chemistry has advanced technical platforms to ensure the accuracy of quantitative results of flavonoids.
- Alfa Chemistry provides industry-approved analysis reports to ensure the authenticity of the data.
- Alfa Chemistry has experienced experts to offer professional advices on flavonoids research.
- Alfa Chemistry has professional and reliable pre-sales and after-sales service that is responsible for the data to the end.
Please contact us if you have questions about flavonoids analysis. We will provide you with professional and high quality flavonoids analysis services.
Ordering Process
Reference
- Dias, M.C.; et al. Plant flavonoids: chemical characteristics and biological activity. Molecules. 2021, 26(17): 5377.
Please kindly note that our products and services are for research use only.
